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Trials Terminated Due To Poor Enrollment Are Four Times More Likely To Involve A Marketed Therapy Versus A Novel Drug
Trial termination is a natural consequence of clinical development, with the largest numbers of trial terminations occuring at Phase II. In the November issue of
Sexual Problems In Women Prevalent But Not Always Associated With Distress
The largest such study ever published finds that, while about 40 percent of women surveyed report having sexual problems, only 12 percent indicate that those issues are a source of significant personal distress. The report led by a Massachusetts General Hospital (MGH) physician appears in the November issue of Obstetrics & Gynecology.
Repligen Announces Publication Of Positive Results With Proprietary HDAC Inhibitor In Huntington's Disease Model
Repligen Corporation (Nasdaq: RGEN) reported publication of a preclinical study demonstrating that a novel histone deacetylase (HDAC) inhibitor improved disease symptoms in a transgenic animal model of Huntington's disease. The study, led by scientists at The Scripps Research Institute, demonstrated that oral administration of the drug candidate to the mice after the onset of symptoms slowed the progression of disease.